SOX9 gene transfer via safe, stable, replication-defective recombinant adeno-associated virus vectors as a novel, powerful tool to enhance the chondrogenic potential of human mesenchymal stem cells

INTRODUCTION: Transplantation of genetically modified human bone marrow-derived mesenchymal stem cells (hMSCs) with an accurate potential for chondrogenic differentiation may be a powerful means to enhance the healing of articular cartilage lesions in patients. Here, we evaluated the benefits of del...

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Detalles Bibliográficos
Autores principales: Venkatesan, Jagadeesh K, Ekici, Myriam, Madry, Henning, Schmitt, Gertrud, Kohn, Dieter, Cucchiarini, Magali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583131/
https://www.ncbi.nlm.nih.gov/pubmed/22742415
http://dx.doi.org/10.1186/scrt113

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