Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments

BACKGROUND: Treatment of solid tumors with vascular disrupting agent OXi4503 results in over 90% tumor destruction. However, a thin rim of viable cells persists in the tumor periphery following treatment, contributing to subsequent recurrence. This study investigates inherent differences in the micr...

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Detalles Bibliográficos
Autores principales: Nguyen, Linh, Fifis, Theodora, Malcontenti-Wilson, Caterina, Chan, Lie Sam, Costa, Patricia Nunes Luiza, Nikfarjam, Mehrdad, Muralidharan, Vijayaragavan, Christophi, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583184/
https://www.ncbi.nlm.nih.gov/pubmed/23153292
http://dx.doi.org/10.1186/1471-2407-12-522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583184/
https://www.ncbi.nlm.nih.gov/pubmed/23153292
http://dx.doi.org/10.1186/1471-2407-12-522

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