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Novel HER2 Aptamer Selectively Delivers Cytotoxic Drug to HER2-positive Breast Cancer Cells in Vitro
BACKGROUND: Aptamer-based tumor targeted drug delivery system is a promising approach that may increase the efficacy of chemotherapy and reduce the related toxicity. HER2 protein is an attractive target for tumor-specific drug delivery because of its overexpression in multiple malignancies, includin...
Autores principales: | Liu, Zhe, Duan, Jin-Hong, Song, Yong-Mei, Ma, Jie, Wang, Feng-Dan, Lu, Xin, Yang, Xian-Da |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583217/ https://www.ncbi.nlm.nih.gov/pubmed/22817844 http://dx.doi.org/10.1186/1479-5876-10-148 |
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