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Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications
Personalized medicine (PM) is currently a hot topic in the professional world. It is often called the medicine of the future and has already achieved resounding success in the area of targeted therapy. Nevertheless, integration of the concepts of PM into routine clinical practice is slow. This revie...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583264/ https://www.ncbi.nlm.nih.gov/pubmed/23471146 http://dx.doi.org/10.4137/BMI.S11153 |
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author | Schmalfuss, F. Kolominsky-Rabas, P.L. |
author_facet | Schmalfuss, F. Kolominsky-Rabas, P.L. |
author_sort | Schmalfuss, F. |
collection | PubMed |
description | Personalized medicine (PM) is currently a hot topic in the professional world. It is often called the medicine of the future and has already achieved resounding success in the area of targeted therapy. Nevertheless, integration of the concepts of PM into routine clinical practice is slow. This review is intended to give an overview of current and potential applications of PM in oncology. PM could soon play a decisive role, especially in screening. The relevance of PM in screening was examined in the case of four common cancers (colorectal cancer, lung cancer, breast cancer, and prostate cancer). A literature search was performed. This showed that biomarkers in particular play a crucial role in screening. In summary, it can be emphasized that there are already numerous known promising biomarkers in malignant disease. This results in several possibilities for individualizing and revolutionizing screening. |
format | Online Article Text |
id | pubmed-3583264 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-35832642013-03-07 Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications Schmalfuss, F. Kolominsky-Rabas, P.L. Biomark Insights Review Personalized medicine (PM) is currently a hot topic in the professional world. It is often called the medicine of the future and has already achieved resounding success in the area of targeted therapy. Nevertheless, integration of the concepts of PM into routine clinical practice is slow. This review is intended to give an overview of current and potential applications of PM in oncology. PM could soon play a decisive role, especially in screening. The relevance of PM in screening was examined in the case of four common cancers (colorectal cancer, lung cancer, breast cancer, and prostate cancer). A literature search was performed. This showed that biomarkers in particular play a crucial role in screening. In summary, it can be emphasized that there are already numerous known promising biomarkers in malignant disease. This results in several possibilities for individualizing and revolutionizing screening. Libertas Academica 2013-02-18 /pmc/articles/PMC3583264/ /pubmed/23471146 http://dx.doi.org/10.4137/BMI.S11153 Text en © 2013 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article. Unrestricted non-commercial use is permitted provided the original work is properly cited. |
spellingShingle | Review Schmalfuss, F. Kolominsky-Rabas, P.L. Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title | Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title_full | Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title_fullStr | Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title_full_unstemmed | Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title_short | Personalized Medicine in Screening for Malignant Disease: A Review of Methods and Applications |
title_sort | personalized medicine in screening for malignant disease: a review of methods and applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583264/ https://www.ncbi.nlm.nih.gov/pubmed/23471146 http://dx.doi.org/10.4137/BMI.S11153 |
work_keys_str_mv | AT schmalfussf personalizedmedicineinscreeningformalignantdiseaseareviewofmethodsandapplications AT kolominskyrabaspl personalizedmedicineinscreeningformalignantdiseaseareviewofmethodsandapplications |