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Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population
BACKGROUND: Epidemiology and animal models suggest that dietary monosodium glutamate (MSG) may contribute to the onset of obesity and the metabolic syndrome. METHODS: Families (n = 324) from a rural area of Thailand were selected and provided MSG as the sole source for the use in meal preparation fo...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583269/ https://www.ncbi.nlm.nih.gov/pubmed/22681873 http://dx.doi.org/10.1186/1743-7075-9-50 |
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author | Insawang, Tonkla Selmi, Carlo Cha’on, Ubon Pethlert, Supattra Yongvanit, Puangrat Areejitranusorn, Premjai Boonsiri, Patcharee Khampitak, Tueanjit Tangrassameeprasert, Roongpet Pinitsoontorn, Chadamas Prasongwattana, Vitoon Gershwin, M Eric Hammock, Bruce D |
author_facet | Insawang, Tonkla Selmi, Carlo Cha’on, Ubon Pethlert, Supattra Yongvanit, Puangrat Areejitranusorn, Premjai Boonsiri, Patcharee Khampitak, Tueanjit Tangrassameeprasert, Roongpet Pinitsoontorn, Chadamas Prasongwattana, Vitoon Gershwin, M Eric Hammock, Bruce D |
author_sort | Insawang, Tonkla |
collection | PubMed |
description | BACKGROUND: Epidemiology and animal models suggest that dietary monosodium glutamate (MSG) may contribute to the onset of obesity and the metabolic syndrome. METHODS: Families (n = 324) from a rural area of Thailand were selected and provided MSG as the sole source for the use in meal preparation for 10 days. Three hundred forty-nine subjects aged 35–55 years completed the study and were evaluated for energy and nutrient intake, physical activity, and tobacco smoking. The prevalence of overweight and obesity (BMI ≥ 25 kg/m(2)), insulin resistance (HOMA-IR >3), and the metabolic syndrome (ATP III criteria) were evaluated according to the daily MSG intake. RESULTS: The prevalence of the metabolic syndrome was significantly higher in the tertile with the highest MSG intake. Further, every 1 g increase in MSG intake significantly increased the risk of having the metabolic syndrome (odds ratio 1.14, 95% confidence interval-CI- 1.12 - 1.28) or being overweight (odds ratio 1.16, 95% CI 1.04 - 1.29), independent of the total energy intake and the level of physical activity. CONCLUSION: Higher amounts of individual MSG consumption are associated with the risk of having the metabolic syndrome and being overweight independent of other major determinants. |
format | Online Article Text |
id | pubmed-3583269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35832692013-02-28 Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population Insawang, Tonkla Selmi, Carlo Cha’on, Ubon Pethlert, Supattra Yongvanit, Puangrat Areejitranusorn, Premjai Boonsiri, Patcharee Khampitak, Tueanjit Tangrassameeprasert, Roongpet Pinitsoontorn, Chadamas Prasongwattana, Vitoon Gershwin, M Eric Hammock, Bruce D Nutr Metab (Lond) Research BACKGROUND: Epidemiology and animal models suggest that dietary monosodium glutamate (MSG) may contribute to the onset of obesity and the metabolic syndrome. METHODS: Families (n = 324) from a rural area of Thailand were selected and provided MSG as the sole source for the use in meal preparation for 10 days. Three hundred forty-nine subjects aged 35–55 years completed the study and were evaluated for energy and nutrient intake, physical activity, and tobacco smoking. The prevalence of overweight and obesity (BMI ≥ 25 kg/m(2)), insulin resistance (HOMA-IR >3), and the metabolic syndrome (ATP III criteria) were evaluated according to the daily MSG intake. RESULTS: The prevalence of the metabolic syndrome was significantly higher in the tertile with the highest MSG intake. Further, every 1 g increase in MSG intake significantly increased the risk of having the metabolic syndrome (odds ratio 1.14, 95% confidence interval-CI- 1.12 - 1.28) or being overweight (odds ratio 1.16, 95% CI 1.04 - 1.29), independent of the total energy intake and the level of physical activity. CONCLUSION: Higher amounts of individual MSG consumption are associated with the risk of having the metabolic syndrome and being overweight independent of other major determinants. BioMed Central 2012-06-08 /pmc/articles/PMC3583269/ /pubmed/22681873 http://dx.doi.org/10.1186/1743-7075-9-50 Text en Copyright © 2012 Insawang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Insawang, Tonkla Selmi, Carlo Cha’on, Ubon Pethlert, Supattra Yongvanit, Puangrat Areejitranusorn, Premjai Boonsiri, Patcharee Khampitak, Tueanjit Tangrassameeprasert, Roongpet Pinitsoontorn, Chadamas Prasongwattana, Vitoon Gershwin, M Eric Hammock, Bruce D Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title | Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title_full | Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title_fullStr | Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title_full_unstemmed | Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title_short | Monosodium glutamate (MSG) intake is associated with the prevalence of metabolic syndrome in a rural Thai population |
title_sort | monosodium glutamate (msg) intake is associated with the prevalence of metabolic syndrome in a rural thai population |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583269/ https://www.ncbi.nlm.nih.gov/pubmed/22681873 http://dx.doi.org/10.1186/1743-7075-9-50 |
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