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Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer’s disease: a stochastic modelling approach

BACKGROUND: Alzheimer’s disease (AD) is the most frequently diagnosed neurodegenerative disorder affecting humans, with advanced age being the most prominent risk factor for developing AD. Despite intense research efforts aimed at elucidating the precise molecular underpinnings of AD, a definitive a...

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Detalles Bibliográficos
Autores principales:	Proctor, Carole J, Pienaar, Ilse Sanet, Elson, Joanna L, Kirkwood, Thomas BL
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583291/ https://www.ncbi.nlm.nih.gov/pubmed/22748062 http://dx.doi.org/10.1186/1750-1326-7-32

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