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Chemotherapy and skin reactions
BACKGROUND: New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients’ quality of life. Appropriate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583303/ https://www.ncbi.nlm.nih.gov/pubmed/22640460 http://dx.doi.org/10.1186/1756-9966-31-50 |
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author | Fabbrocini, Gabriella Cameli, Norma Romano, Maria Concetta Mariano, Maria Panariello, Luigia Bianca, Dario Monfrecola, Giuseppe |
author_facet | Fabbrocini, Gabriella Cameli, Norma Romano, Maria Concetta Mariano, Maria Panariello, Luigia Bianca, Dario Monfrecola, Giuseppe |
author_sort | Fabbrocini, Gabriella |
collection | PubMed |
description | BACKGROUND: New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients’ quality of life. Appropriate management of skin toxicity associated with chemotherapic agents is therefore necessary for suitable drug administration and to improve quality of life and clinical outcomes. METHODS: We have clinically examined 100 patients affected by cancer, determining type, frequency, treatment, and evolution of side effects related to chemotherapy. RESULTS: The prevalent cutaneous side effects in patients undergoing chemotherapy are skin rash, xerosis, pruritus, paronychia, hair abnormality, and mucositis. The clinical cases are reported in detail. CONCLUSION: Oncological therapies have become more selective and have low systemic toxicity because of their high specificity, but cutaneous side effects are common and may worsen the quality of life of these patients. |
format | Online Article Text |
id | pubmed-3583303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35833032013-02-28 Chemotherapy and skin reactions Fabbrocini, Gabriella Cameli, Norma Romano, Maria Concetta Mariano, Maria Panariello, Luigia Bianca, Dario Monfrecola, Giuseppe J Exp Clin Cancer Res Research BACKGROUND: New chemotherapic agents and new protocols in oncology have led to an increasing survival rate in patients affected by tumors. However, this increased use has been accompanied by a growth in the incidence of cutaneous side effects and a worsening of patients’ quality of life. Appropriate management of skin toxicity associated with chemotherapic agents is therefore necessary for suitable drug administration and to improve quality of life and clinical outcomes. METHODS: We have clinically examined 100 patients affected by cancer, determining type, frequency, treatment, and evolution of side effects related to chemotherapy. RESULTS: The prevalent cutaneous side effects in patients undergoing chemotherapy are skin rash, xerosis, pruritus, paronychia, hair abnormality, and mucositis. The clinical cases are reported in detail. CONCLUSION: Oncological therapies have become more selective and have low systemic toxicity because of their high specificity, but cutaneous side effects are common and may worsen the quality of life of these patients. BioMed Central 2012-05-28 /pmc/articles/PMC3583303/ /pubmed/22640460 http://dx.doi.org/10.1186/1756-9966-31-50 Text en Copyright ©2012 Fabbrocini et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Fabbrocini, Gabriella Cameli, Norma Romano, Maria Concetta Mariano, Maria Panariello, Luigia Bianca, Dario Monfrecola, Giuseppe Chemotherapy and skin reactions |
title | Chemotherapy and skin reactions |
title_full | Chemotherapy and skin reactions |
title_fullStr | Chemotherapy and skin reactions |
title_full_unstemmed | Chemotherapy and skin reactions |
title_short | Chemotherapy and skin reactions |
title_sort | chemotherapy and skin reactions |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583303/ https://www.ncbi.nlm.nih.gov/pubmed/22640460 http://dx.doi.org/10.1186/1756-9966-31-50 |
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