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Mature Microsatellites: Mechanisms Underlying Dinucleotide Microsatellite Mutational Biases in Human Cells

Dinucleotide microsatellites are dynamic DNA sequences that affect genome stability. Here, we focused on mature microsatellites, defined as pure repeats of lengths above the threshold and unlikely to mutate below it in a single mutational event. We investigated the prevalence and mutational behavior...

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Detalles Bibliográficos
Autores principales: Baptiste, Beverly A., Ananda, Guruprasad, Strubczewski, Noelle, Lutzkanin, Andrew, Khoo, Su Jen, Srikanth, Abhinaya, Kim, Nari, Makova, Kateryna D., Krasilnikova, Maria M., Eckert, Kristin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583453/
https://www.ncbi.nlm.nih.gov/pubmed/23450065
http://dx.doi.org/10.1534/g3.112.005173