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Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells

Using seven monoclonal SN38-resistant subclones established from ME180 human cervical squamous cell carcinoma cells, we examined the demethylation effects of 5-aza-2′-deoxycytidine (5-aza-CdR) on the SN38-sensitivity of the cells as well as the expression of death-associated protein kinase (DAPK) in...

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Detalles Bibliográficos
Autores principales: TANAKA, TETSUJI, BAI, TAO, TOUJIMA, SAORI, UTSUNOMIYA, TOMOKO, MATSUOKA, TOSHIHIDE, KOBAYASHI, AYA, YAMAMOTO, MADOKA, SASAKI, NORIYUKI, TANIZAKI, YUKO, UTSUNOMIYA, HIROTOSHI, TANAKA, JUNKO, YUKAWA, KAZUNORI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583479/
https://www.ncbi.nlm.nih.gov/pubmed/22246465
http://dx.doi.org/10.3892/or.2012.1628