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53BP1 suppresses tumor growth and promotes susceptibility to apoptosis of ovarian cancer cells through modulation of the Akt pathway

53BP1 has been extensively studied as a key component of the DNA damage response, but little is known regarding the role of 53BP1 in preventing tumor development. The present study was designed to assess the impact of the modification of 53BP1 gene expression on the biological behavior of ovarian ca...

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Detalles Bibliográficos
Autores principales: HONG, SHUHUI, LI, XIAOYAN, ZHAO, YING, YANG, QIFENG, KONG, BEIHUA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583484/
https://www.ncbi.nlm.nih.gov/pubmed/22266878
http://dx.doi.org/10.3892/or.2012.1641