Promoter methylation of MGMT, MLH1 and RASSF1A tumor suppressor genes in head and neck squamous cell carcinoma: Pharmacological genome demethylation reduces proliferation of head and neck squamous carcinoma cells

Promoter hypermethylation of tumor suppressor genes (TSGs) is a common feature of primary cancer cells. However, to date the somatic epigenetic events that occur in head and neck squamous cell carcinoma (HNSCC) tumorigenesis have not been well-defined. In the present study, we analyzed the promoter...

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Detalles Bibliográficos
Autores principales: KOUTSIMPELAS, DIMITRIOS, PONGSAPICH, WARUT, HEINRICH, ULF, MANN, SYLVIA, MANN, WOLF J., BRIEGER, JÜRGEN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583513/
https://www.ncbi.nlm.nih.gov/pubmed/22246327
http://dx.doi.org/10.3892/or.2012.1624

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