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Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma
N(1),N(11)-diethylnorspermine (DENSPM), a polyamine analog that induces expression of spermidine/spermine N(1)-acetyltransferase (SSAT) and reduces polyamine levels in eukaryotic cells, has demonstrated anticancer effects in many cancer cell types. Gene expression of SSAT after treatment with DENSPM...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583519/ https://www.ncbi.nlm.nih.gov/pubmed/22179681 http://dx.doi.org/10.3892/or.2011.1592 |