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Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

N(1),N(11)-diethylnorspermine (DENSPM), a polyamine analog that induces expression of spermidine/spermine N(1)-acetyltransferase (SSAT) and reduces polyamine levels in eukaryotic cells, has demonstrated anticancer effects in many cancer cell types. Gene expression of SSAT after treatment with DENSPM...

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Detalles Bibliográficos
Autores principales: TIAN, YE, WANG, SHIZHAO, WANG, BIN, ZHANG, JIANNING, JIANG, RONGCAI, ZHANG, WEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583519/
https://www.ncbi.nlm.nih.gov/pubmed/22179681
http://dx.doi.org/10.3892/or.2011.1592

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