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The effects of cyclooxygenase-2 gene silencing by siRNA on cell proliferation, cell apoptosis, cell cycle and tumorigenicity of Capan-2 human pancreatic cancer cells

The prognosis of pancreatic cancer is still very poor. No specific effective gene therapy for pancreatic cancer has been found. As a key enzyme of the metabolic process of arachidonic acid, cyclooxygenase-2 (COX-2) has been found to be closely related to the tumorigenesis of epithelial cancers. Howe...

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Detalles Bibliográficos
Autores principales: ZHONG, YINGQIANG, XIA, ZHONGSHENG, LIU, JUAN, LIN, YING, ZAN, HUI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583541/
https://www.ncbi.nlm.nih.gov/pubmed/22200969
http://dx.doi.org/10.3892/or.2011.1595