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Downregulation of indoleamine-2,3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation

This study examined the role of the immunosuppressive enzyme indoleamine-2,3-dioxygenase (IDO) in cervical cancer progression and the possible use of this enzyme for cervical cancer therapy. We analyzed IDO protein expression in 9 cervical cancer cell lines (SKG-I, -II, -IIIa, -IIIb, SiHa, CaSki, BO...

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Detalles Bibliográficos
Autores principales: SATO, NAOTO, SAGA, YASUSHI, MIZUKAMI, HIROAKI, WANG, DONGDONG, TAKAHASHI, SUZUYO, NONAKA, HIROAKI, FUJIWARA, HIROYUKI, TAKEI, YUJI, MACHIDA, SHIZUO, TAKIKAWA, OSAMU, OZAWA, KEIYA, SUZUKI, MITSUAKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583609/
https://www.ncbi.nlm.nih.gov/pubmed/22923135
http://dx.doi.org/10.3892/or.2012.1984