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Epigenetic silencing of miR-335 and its host gene MEST in hepatocellular carcinoma

MicroRNAs (miRNAs) are small non-coding RNAs that function as endogenous silencers of target genes. Some tumor-suppressive miRNAs are known to be epigenetically silenced by promoter DNA methylation in cancer. In the present study, we aimed to identify miRNA genes that are silenced by DNA hypermethyl...

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Detalles Bibliográficos
Autores principales:	DOHI, OSAMU, YASUI, KOHICHIROH, GEN, YASUYUKI, TAKADA, HISASHI, ENDO, MIO, TSUJI, KAZUHIRO, KONISHI, CHIKA, YAMADA, NOBUHISA, MITSUYOSHI, HIRONORI, YAGI, NOBUAKI, NAITO, YUJI, TANAKA, SHINJI, ARII, SHIGEKI, YOSHIKAWA, TOSHIKAZU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583616/ https://www.ncbi.nlm.nih.gov/pubmed/23229728 http://dx.doi.org/10.3892/ijo.2012.1724

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