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γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products
Taxanes, including docetaxel, are widely used for the treatment of squamous cell carcinoma of the head and neck. However, the gastrointestinal toxicity of docetaxel has limited its high-dose clinical use. In this study, we examined the synergistic anticancer effects of combined low-dose docetaxel an...
Autores principales: | KANI, KOUICHI, MOMOTA, YUKIHIRO, HARADA, MICHITO, YAMAMURA, YOSHIKO, AOTA, KEIKO, YAMANOI, TOMOKO, TAKANO, HIDEYUKI, MOTEGI, KATSUMI, AZUMA, MASAYUKI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583629/ https://www.ncbi.nlm.nih.gov/pubmed/23138939 http://dx.doi.org/10.3892/ijo.2012.1692 |
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