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PECAM-1 is involved in BCR/ABL signaling and may downregulate imatinib-induced apoptosis of Philadelphia chromosome-positive leukemia cells

PECAM-1 (CD31) is an immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing surface glycoprotein expressed on various hematopoietic cells as well as on endothelial cells. PECAM-1 has been shown to play roles in regulation of adhesion, migration and apoptosis. The BCR/ABL fusion tyrosine ki...

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Detalles Bibliográficos
Autores principales:	WU, NAN, KUROSU, TETSUYA, OSHIKAWA, GAKU, NAGAO, TOSHIKAGE, MIURA, OSAMU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583636/ https://www.ncbi.nlm.nih.gov/pubmed/23233201 http://dx.doi.org/10.3892/ijo.2012.1729

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