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CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells
We have recently unravelled a novel function for CD82 in E-cadherin-mediated cellular adhesion. CD82 inhibits β-catenin tyrosine phosphorylation and stabilizes E-cadherin-β-catenin complexes at the cell membrane. This function inhibits cancer cell dissociation from the primary cancer nest and limits...
Autores principales: | CHIGITA, SATOMI, SUGIURA, TSUYOSHI, ABE, MASAKAZU, KOBAYASHI, YOSUKE, SHIMODA, MIYUKI, ONODA, MEGUMI, SHIRASUNA, KANEMITSU |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583648/ https://www.ncbi.nlm.nih.gov/pubmed/23076981 http://dx.doi.org/10.3892/ijo.2012.1671 |
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