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CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells

We have recently unravelled a novel function for CD82 in E-cadherin-mediated cellular adhesion. CD82 inhibits β-catenin tyrosine phosphorylation and stabilizes E-cadherin-β-catenin complexes at the cell membrane. This function inhibits cancer cell dissociation from the primary cancer nest and limits...

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Detalles Bibliográficos
Autores principales:	CHIGITA, SATOMI, SUGIURA, TSUYOSHI, ABE, MASAKAZU, KOBAYASHI, YOSUKE, SHIMODA, MIYUKI, ONODA, MEGUMI, SHIRASUNA, KANEMITSU
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583648/ https://www.ncbi.nlm.nih.gov/pubmed/23076981 http://dx.doi.org/10.3892/ijo.2012.1671

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