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Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells

BACKGROUND: Post-translational modifications (PTMs) of histones and other proteins are perturbed in tumours. For example, reduced levels of acetylated H4K16 and trimethylated H4K20 are associated with high tumour grade and poor survival in breast cancer. Drug-like molecules that can reprogram select...

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Detalles Bibliográficos
Autores principales:	Collins, Hilary M, Abdelghany, Magdy K, Messmer, Marie, Yue, Baigong, Deeves, Sian E, Kindle, Karin B, Mantelingu, Kempegowda, Aslam, Akhmed, Winkler, G Sebastiaan, Kundu, Tapas K, Heery, David M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583671/ https://www.ncbi.nlm.nih.gov/pubmed/23356739 http://dx.doi.org/10.1186/1471-2407-13-37

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