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Antipsychotic medications and cognitive functioning in bipolar disorder: moderating effects of COMT Val(108/158) Met genotype

BACKGROUND: There is a negative association between the use of antipsychotics and cognitive functioning in bipolar patients, which may be mediated by altered dopamine signaling in selected brain areas, and moderation thereof by genetic sequence variation such as COMT Val(108/158)Met. The interaction...

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Detalles Bibliográficos
Autores principales: Arts, Baer, Simons, Claudia JP, Drukker, Marjan, van Os, Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583705/
https://www.ncbi.nlm.nih.gov/pubmed/23421957
http://dx.doi.org/10.1186/1471-244X-13-63