Cargando…

Centrosomal localization of RhoGDIβ and its relevance to mitotic processes in cancer cells

Rho GDP-dissociation inhibitors (RhoGDIs) are regulators of Rho family GTPases. RhoGDIβ has been implicated in cancer progression, but its precise role remains unclear. We determined the subcellular localization of RhoGDIβ and examined the effects of its overexpression and RNAi knockdown in cancer c...

Descripción completa

Detalles Bibliográficos
Autores principales:	JIANG, YONG-SHENG, MAEDA, MASAYO, OKAMOTO, MAYUMI, FUJII, MIKIKO, FUKUTOMI, RYUICHIRO, HORI, MASATO, TATSUKA, MASAAKI, OTA, TAKAHIDE
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583720/ https://www.ncbi.nlm.nih.gov/pubmed/23232495 http://dx.doi.org/10.3892/ijo.2012.1730

Ejemplares similares

Positive regulation of Rho GTPase activity by RhoGDIs as a result of their direct interaction with GAPs
por: Ota, Takahide, et al.
Publicado: (2015)

Apoptosis-independent cleavage of RhoGDIβ at Asp19 during PMA-stimulated differentiation of THP-1 cells to macrophages
por: Ota, Takahide, et al.
Publicado: (2017)

The Dual Function of RhoGDI2 in Immunity and Cancer
por: Tripathi, Mudrika, et al.
Publicado: (2023)

Regulation of RhoGTPase crosstalk, degradation and activity by RhoGDI1
por: Boulter, Etienne, et al.
Publicado: (2010)

A Review on the Function and Regulation of ARHGDIB/RhoGDI2 Expression Including the Hypothetical Role of ARHGDIB/RhoGDI2 Autoantibodies in Kidney Transplantation
por: Kardol-Hoefnagel, Tineke, et al.
Publicado: (2020)

Rictor regulates cell migration by suppressing RhoGDI2
por: Agarwal, Nitin K., et al.
Publicado: (2012)

Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
por: Golding, Adriana E, et al.
Publicado: (2019)

Protein expression in human trabecular meshwork: downregulation of RhoGDI by dexamethasone in vitro
por: Yu, Minbin, et al.
Publicado: (2010)

RhoGDIα suppresses self-renewal and tumorigenesis of glioma stem cells
por: Wu, Fan, et al.
Publicado: (2016)

PKCα phosphorylation of RhoGDI2 at Ser 31 disrupts interactions with Rac1 and decreases GDI activity
por: Griner, Erin M., et al.
Publicado: (2012)

Protein Kinase A Governs a RhoA-RhoGDI Protrusion-Retraction Pacemaker in Migrating Cells
por: Tkachenko, Eugene, et al.
Publicado: (2011)

RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment
por: Said, Neveen, et al.
Publicado: (2012)

Adenosine Inhibits Ovarian Cancer Growth Through Regulating RhoGDI2 Protein Expression
por: Xia, Bing, et al.
Publicado: (2019)

CRIF1 deficiency suppresses endothelial cell migration via upregulation of RhoGDI2
por: Nagar, Harsha, et al.
Publicado: (2021)

A Complete Survey of RhoGDI Targets Reveals Novel Interactions with Atypical Small GTPases
por: Ahmad Mokhtar, Ana Masara binti, et al.
Publicado: (2021)

RhoGDIα regulates spermatogenesis through Rac1/cofilin/F-actin signaling
por: Zhu, Haixia, et al.
Publicado: (2023)

RhoGDIα-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis
por: Giang Ho, T. T., et al.
Publicado: (2011)

Cholecystokinin-Mediated RhoGDI Phosphorylation via PKCα Promotes both RhoA and Rac1 Signaling
por: Sabbatini, Maria Eugenia, et al.
Publicado: (2013)

RhoGDI deficiency induces constitutive activation of Rho GTPases and COX-2 pathways in association with breast cancer progression
por: Bozza, William P., et al.
Publicado: (2015)

RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells
por: Cho, Hee Jun, et al.
Publicado: (2014)

CPK3-phosphorylated RhoGDI1 is essential in the development of Arabidopsis seedlings and leaf epidermal cells
por: Wu, Yuxuan, et al.
Publicado: (2013)

EphrinB1 promotes cancer cell migration and invasion through the interaction with RhoGDI1
por: Cho, H J, et al.
Publicado: (2018)

Activating Transcription Factor 4 (ATF4) modulates Rho GTPase levels and function via regulation of RhoGDIα
por: Pasini, Silvia, et al.
Publicado: (2016)

Anticarcinogenic Effect and Enhancement of Metastatic Potential of BALB/c 3T3 Cells by Ginsenoside Rh(2)
por: Tatsuka, Masaaki, et al.
Publicado: (2001)

Immunological and Functional Characterization of RhoGDI3 and Its Molecular Targets RhoG and RhoB in Human Pancreatic Cancerous and Normal Cells
por: de León-Bautista, Mercedes Piedad, et al.
Publicado: (2016)

RhoGDIβ-induced hypertrophic growth in H9c2 cells is negatively regulated by ZAK
por: Huang, Chih-Yang, et al.
Publicado: (2009)

ZAK negatively regulates RhoGDIβ-induced Rac1-mediated hypertrophic growth and cell migration
por: Huang, Chih-Yang, et al.
Publicado: (2009)

RhoGDI2 up-regulates P-glycoprotein expression via Rac1 in gastric cancer cells
por: Zheng, Zhong, et al.
Publicado: (2015)

miR-25 promotes hepatocellular carcinoma cell growth, migration and invasion by inhibiting RhoGDI1
por: Wang, Congren, et al.
Publicado: (2015)

FRET biosensor allows spatio-temporal observation of shear stress-induced polar RhoGDIα activation
por: Shao, Shuai, et al.
Publicado: (2018)

Calmodulin Domain Protein Kinase PiCDPK1 Regulates Pollen Tube Growth Polarity through Interaction with RhoGDI
por: Scheible, Nolan, et al.
Publicado: (2022)

Serine 34 Phosphorylation of Rho Guanine Dissociation Inhibitor (RhoGDIα) Links Signaling from Conventional Protein Kinase C to RhoGTPase in Cell Adhesion
por: Dovas, Athanassios, et al.
Publicado: (2010)

Pathological Cyclic Strain-Induced Apoptosis in Human Periodontal Ligament Cells through the RhoGDIα/Caspase-3/PARP Pathway
por: Wang, Li, et al.
Publicado: (2013)

Suppression of RhoG activity is mediated by a syndecan 4–synectin–RhoGDI1 complex and is reversed by PKCα in a Rac1 activation pathway
por: Elfenbein, Arye, et al.
Publicado: (2009)

E3 Ligase Activity of XIAP RING Domain Is Required for XIAP-Mediated Cancer Cell Migration, but Not for Its RhoGDI Binding Activity
por: Liu, Jinyi, et al.
Publicado: (2012)

RhoGDI1-Cdc42 Signaling Is Required for PDGF-BB-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Neointima Formation
por: Qi, Yan, et al.
Publicado: (2021)

Downregulation of miR-483-5p inhibits TGF-β1-induced EMT by targeting RhoGDI1 in pulmonary fibrosis
por: Huang, Guichuan, et al.
Publicado: (2021)

Differential functions of RhoGDIβ in malignant transformation and progression of urothelial cell following N-butyl-N-(4-hydmoxybutyl) nitrosamine exposure
por: Hua, Xiaohui, et al.
Publicado: (2023)

Regulation of Rho GTPases by RhoGDIs in Human Cancers
por: Cho, Hee Jun, et al.
Publicado: (2019)

αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion
por: Reyes, Steve B., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_7uug9gial2kc4p1og6bn8c3blm