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Genetic and epigenetic alterations of steroidogenic factor-1 in ovarian tumors
Steroidogenic factor-1 (SF-1), the product of the NR5A1 gene, is an essential transcription factor that is known to regulate steroidogenesis in ovarian epithelia, including the synthesis of progesterone, a suppressor of ovarian cancer. Expression of the SF-1 protein, a potential ovarian tumor suppre...
Autores principales: | MILLER, SARAH, BHASIN, NOBEL, URREGO, HEATHER, MOROZ, KRZYSZTOF, ROWAN, BRIAN G., RAMAYYA, MEERA S., MAKRIDAKIS, NICK M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583749/ https://www.ncbi.nlm.nih.gov/pubmed/23291911 http://dx.doi.org/10.3892/ijo.2012.1758 |
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