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Determination of the consequences of VHL mutations on VHL transcripts in renal cell carcinoma

Genetic and epigenetic changes in the von Hippel-Lindau (VHL) tumour suppressor gene are common in sporadic conventional (clear cell) renal cell carcinoma (ccRCC). The effects on VHL expression are unknown but increased understanding may be relevant clinically, either in terms of prognosis or in the...

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Detalles Bibliográficos
Autores principales: TAYLOR, CLAIRE, CRAVEN, RACHEL A., HARNDEN, PATRICIA, SELBY, PETER J., BANKS, ROSAMONDE E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583750/
https://www.ncbi.nlm.nih.gov/pubmed/22825683
http://dx.doi.org/10.3892/ijo.2012.1561

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