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β-catenin Is Essential for Efficient In Vitro Premyogenic Mesoderm Formation but Can Be Partially Compensated by Retinoic Acid Signalling

Previous studies have shown that P19 cells expressing a dominant negative β-catenin mutant (β-cat/EnR) cannot undergo myogenic differentiation in the presence or absence of muscle-inducing levels of retinoic acid (RA). While RA could upregulate premyogenic mesoderm expression, including Pax3/7 and M...

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Detalles Bibliográficos
Autores principales:	Wong, Jacob, Mehta, Virja, Voronova, Anastassia, Coutu, Josée, Ryan, Tammy, Shelton, Michael, Skerjanc, Ilona S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583846/ https://www.ncbi.nlm.nih.gov/pubmed/23460868 http://dx.doi.org/10.1371/journal.pone.0057501

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