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UV, stress and aging
Skin is a model of choice in studies on aging. Indeed, skin aging can be modulated by internal and external factors, reflecting its complexity. Two types of skin aging have been identified: intrinsic, mainly genetically determined and extrinsic—also called "photo-aging"—resulting on the im...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583883/ https://www.ncbi.nlm.nih.gov/pubmed/23467762 http://dx.doi.org/10.4161/derm.23652 |
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author | Debacq-Chainiaux, Florence Leduc, Cedric Verbeke, Alix Toussaint, Olivier |
author_facet | Debacq-Chainiaux, Florence Leduc, Cedric Verbeke, Alix Toussaint, Olivier |
author_sort | Debacq-Chainiaux, Florence |
collection | PubMed |
description | Skin is a model of choice in studies on aging. Indeed, skin aging can be modulated by internal and external factors, reflecting its complexity. Two types of skin aging have been identified: intrinsic, mainly genetically determined and extrinsic—also called "photo-aging"—resulting on the impact of environmental stress and more precisely of UV rays. Simplified in vitro models, based on cellular senescence, have been developed to study the relationship between UV and aging. These models vary on the cell type (fibroblasts or keratinocytes, normal or immortalized) and the type of UV used (UVA or UVB). |
format | Online Article Text |
id | pubmed-3583883 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-35838832013-03-06 UV, stress and aging Debacq-Chainiaux, Florence Leduc, Cedric Verbeke, Alix Toussaint, Olivier Dermatoendocrinol Review Skin is a model of choice in studies on aging. Indeed, skin aging can be modulated by internal and external factors, reflecting its complexity. Two types of skin aging have been identified: intrinsic, mainly genetically determined and extrinsic—also called "photo-aging"—resulting on the impact of environmental stress and more precisely of UV rays. Simplified in vitro models, based on cellular senescence, have been developed to study the relationship between UV and aging. These models vary on the cell type (fibroblasts or keratinocytes, normal or immortalized) and the type of UV used (UVA or UVB). Landes Bioscience 2012-07-01 /pmc/articles/PMC3583883/ /pubmed/23467762 http://dx.doi.org/10.4161/derm.23652 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Review Debacq-Chainiaux, Florence Leduc, Cedric Verbeke, Alix Toussaint, Olivier UV, stress and aging |
title | UV, stress and aging |
title_full | UV, stress and aging |
title_fullStr | UV, stress and aging |
title_full_unstemmed | UV, stress and aging |
title_short | UV, stress and aging |
title_sort | uv, stress and aging |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583883/ https://www.ncbi.nlm.nih.gov/pubmed/23467762 http://dx.doi.org/10.4161/derm.23652 |
work_keys_str_mv | AT debacqchainiauxflorence uvstressandaging AT leduccedric uvstressandaging AT verbekealix uvstressandaging AT toussaintolivier uvstressandaging |