NK cell-released exosomes: Natural nanobullets against tumors

We have recently reported that human natural killer (NK) cells release exosomes that express both NK-cell markers and cytotoxic molecules. Similar results were obtained with circulating exosomes from human healthy donors. Both NK-cell derived and circulating exosomes exerted a full functional activi...

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Detalles Bibliográficos
Autor principal: Fais, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583913/
https://www.ncbi.nlm.nih.gov/pubmed/23482694
http://dx.doi.org/10.4161/onci.22337
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author Fais, Stefano
author_facet Fais, Stefano
author_sort Fais, Stefano
collection PubMed
description We have recently reported that human natural killer (NK) cells release exosomes that express both NK-cell markers and cytotoxic molecules. Similar results were obtained with circulating exosomes from human healthy donors. Both NK-cell derived and circulating exosomes exerted a full functional activity and killed both tumor and activated immune cells. These findings indicate that NK-cell derived exosomes might constitute a new promising therapeutic tool.
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spelling pubmed-35839132013-03-11 NK cell-released exosomes: Natural nanobullets against tumors Fais, Stefano Oncoimmunology Author's View We have recently reported that human natural killer (NK) cells release exosomes that express both NK-cell markers and cytotoxic molecules. Similar results were obtained with circulating exosomes from human healthy donors. Both NK-cell derived and circulating exosomes exerted a full functional activity and killed both tumor and activated immune cells. These findings indicate that NK-cell derived exosomes might constitute a new promising therapeutic tool. Landes Bioscience 2013-01-01 /pmc/articles/PMC3583913/ /pubmed/23482694 http://dx.doi.org/10.4161/onci.22337 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Fais, Stefano
NK cell-released exosomes: Natural nanobullets against tumors
title NK cell-released exosomes: Natural nanobullets against tumors
title_full NK cell-released exosomes: Natural nanobullets against tumors
title_fullStr NK cell-released exosomes: Natural nanobullets against tumors
title_full_unstemmed NK cell-released exosomes: Natural nanobullets against tumors
title_short NK cell-released exosomes: Natural nanobullets against tumors
title_sort nk cell-released exosomes: natural nanobullets against tumors
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583913/
https://www.ncbi.nlm.nih.gov/pubmed/23482694
http://dx.doi.org/10.4161/onci.22337
work_keys_str_mv AT faisstefano nkcellreleasedexosomesnaturalnanobulletsagainsttumors

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