The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone

Breast cancer spread to distant sites is often incurable. Our recent findings demonstrate that Type I interferons secreted by tumor cells induce anti-metastatic immune responses that prevent breast cancer metastasis to the bone. This provides novel insights into the importance of the crosstalk betwe...

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Autores principales: Slaney, Clare Y., Möller, Andreas, Hertzog, Paul J., Parker, Belinda S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583915/
https://www.ncbi.nlm.nih.gov/pubmed/23482870
http://dx.doi.org/10.4161/onci.22339
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author Slaney, Clare Y.
Möller, Andreas
Hertzog, Paul J.
Parker, Belinda S.
author_facet Slaney, Clare Y.
Möller, Andreas
Hertzog, Paul J.
Parker, Belinda S.
author_sort Slaney, Clare Y.
collection PubMed
description Breast cancer spread to distant sites is often incurable. Our recent findings demonstrate that Type I interferons secreted by tumor cells induce anti-metastatic immune responses that prevent breast cancer metastasis to the bone. This provides novel insights into the importance of the crosstalk between neoplastic and immune cells in the metastatic process.
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spelling pubmed-35839152013-03-11 The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone Slaney, Clare Y. Möller, Andreas Hertzog, Paul J. Parker, Belinda S. Oncoimmunology Author's View Breast cancer spread to distant sites is often incurable. Our recent findings demonstrate that Type I interferons secreted by tumor cells induce anti-metastatic immune responses that prevent breast cancer metastasis to the bone. This provides novel insights into the importance of the crosstalk between neoplastic and immune cells in the metastatic process. Landes Bioscience 2013-01-01 /pmc/articles/PMC3583915/ /pubmed/23482870 http://dx.doi.org/10.4161/onci.22339 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Slaney, Clare Y.
Möller, Andreas
Hertzog, Paul J.
Parker, Belinda S.
The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title_full The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title_fullStr The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title_full_unstemmed The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title_short The role of Type I interferons in immunoregulation of breast cancer metastasis to the bone
title_sort role of type i interferons in immunoregulation of breast cancer metastasis to the bone
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583915/
https://www.ncbi.nlm.nih.gov/pubmed/23482870
http://dx.doi.org/10.4161/onci.22339
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