Predicting the efficacy of cancer vaccines by evaluating T-cell responses

In a preclinical experimental model of human papilloma virus (HPV)-induced cervical carcinoma, we have shown that the efficacy of cancer vaccines can be predicted by the evaluation of vaccine-induced T-cell responses in healthy subjects. We argue that such knowledge can be used to screen candidates...

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Detalles Bibliográficos
Autores principales: van Duikeren, Suzanne, Arens, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583929/
https://www.ncbi.nlm.nih.gov/pubmed/23482345
http://dx.doi.org/10.4161/onci.22616
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author van Duikeren, Suzanne
Arens, Ramon
author_facet van Duikeren, Suzanne
Arens, Ramon
author_sort van Duikeren, Suzanne
collection PubMed
description In a preclinical experimental model of human papilloma virus (HPV)-induced cervical carcinoma, we have shown that the efficacy of cancer vaccines can be predicted by the evaluation of vaccine-induced T-cell responses in healthy subjects. We argue that such knowledge can be used to screen candidates for vaccination, which in turn may accelerate the development and increase the overall efficacy of cancer vaccines.
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spelling pubmed-35839292013-03-11 Predicting the efficacy of cancer vaccines by evaluating T-cell responses van Duikeren, Suzanne Arens, Ramon Oncoimmunology Author's View In a preclinical experimental model of human papilloma virus (HPV)-induced cervical carcinoma, we have shown that the efficacy of cancer vaccines can be predicted by the evaluation of vaccine-induced T-cell responses in healthy subjects. We argue that such knowledge can be used to screen candidates for vaccination, which in turn may accelerate the development and increase the overall efficacy of cancer vaccines. Landes Bioscience 2013-01-01 /pmc/articles/PMC3583929/ /pubmed/23482345 http://dx.doi.org/10.4161/onci.22616 Text en Copyright © 2013 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
van Duikeren, Suzanne
Arens, Ramon
Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title_full Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title_fullStr Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title_full_unstemmed Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title_short Predicting the efficacy of cancer vaccines by evaluating T-cell responses
title_sort predicting the efficacy of cancer vaccines by evaluating t-cell responses
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583929/
https://www.ncbi.nlm.nih.gov/pubmed/23482345
http://dx.doi.org/10.4161/onci.22616
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