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Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation
The ability of T cells to recognize a vast array of antigens enables them to destroy tumor cells while inflicting minimal collateral damage. Nevertheless, tumor antigens often are a form of self-antigen, and thus tumor immunity can be dampened by tolerance mechanisms that evolved to prevent autoimmu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583935/ https://www.ncbi.nlm.nih.gov/pubmed/23482891 http://dx.doi.org/10.4161/onci.22837 |