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Vemurafenib enhances MHC induction in BRAF(V600E) homozygous melanoma cells

To optimally integrate targeted kinase inhibitors and immunotherapies in the treatment of melanoma, it will be critical to understand how BRAF(V600E) mutational status and BRAF(V600E) inhibition influence the expression of genes that govern antitumor immune responses. Because major histocompatibilit...

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Detalles Bibliográficos
Autores principales: Sapkota, Bishu, Hill, Charles E., Pollack, Brian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583938/
https://www.ncbi.nlm.nih.gov/pubmed/23483066
http://dx.doi.org/10.4161/onci.22890