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Estimating Selection Coefficients in Spatially Structured Populations from Time Series Data of Allele Frequencies
Inferring the nature and magnitude of selection is an important problem in many biological contexts. Typically when estimating a selection coefficient for an allele, it is assumed that samples are drawn from a panmictic population and that selection acts uniformly across the population. However, the...
Autores principales: | Mathieson, Iain, McVean, Gil |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584010/ https://www.ncbi.nlm.nih.gov/pubmed/23307902 http://dx.doi.org/10.1534/genetics.112.147611 |
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