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In Silico Estimation of Translation Efficiency in Human Cell Lines: Potential Evidence for Widespread Translational Control

Recently large scale transcriptome and proteome datasets for human cells have become available. A striking finding from these studies is that the level of an mRNA typically predicts no more than 40% of the abundance of protein. This correlation represents the overall figure for all genes. We present...

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Detalles Bibliográficos
Autores principales: Stevens, Stewart G., Brown, Chris M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584024/
https://www.ncbi.nlm.nih.gov/pubmed/23460887
http://dx.doi.org/10.1371/journal.pone.0057625