Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype

In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.

Detalles Bibliográficos
Autores principales: Izzo, Giselle, Forlenza, Orestes V., dos Santos, Bernardo, Bertolucci, Paulo H. F., Ojopi, Elida B., Gattaz, Wagner F., Kerr, Daniel Shikanai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584260/
https://www.ncbi.nlm.nih.gov/pubmed/23525328
http://dx.doi.org/10.6061/clinics/2013(02)RC01
Descripción
Sumario:In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.

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