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Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype
In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele.
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584260/ https://www.ncbi.nlm.nih.gov/pubmed/23525328 http://dx.doi.org/10.6061/clinics/2013(02)RC01 |
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author | Izzo, Giselle Forlenza, Orestes V. dos Santos, Bernardo Bertolucci, Paulo H. F. Ojopi, Elida B. Gattaz, Wagner F. Kerr, Daniel Shikanai |
author_facet | Izzo, Giselle Forlenza, Orestes V. dos Santos, Bernardo Bertolucci, Paulo H. F. Ojopi, Elida B. Gattaz, Wagner F. Kerr, Daniel Shikanai |
author_sort | Izzo, Giselle |
collection | PubMed |
description | In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele. |
format | Online Article Text |
id | pubmed-3584260 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo |
record_format | MEDLINE/PubMed |
spelling | pubmed-35842602013-03-01 Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype Izzo, Giselle Forlenza, Orestes V. dos Santos, Bernardo Bertolucci, Paulo H. F. Ojopi, Elida B. Gattaz, Wagner F. Kerr, Daniel Shikanai Clinics (Sao Paulo) Rapid Communication In this study, we investigated the associations between single-nucleotide polymorphisms in GAB2 (rs2373115), GSK3B (rs6438552) and SORL1 (rs641120) and Alzheimer's disease (AD), both alone and in combination with the APOE*4 allele. Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo 2013-02 /pmc/articles/PMC3584260/ /pubmed/23525328 http://dx.doi.org/10.6061/clinics/2013(02)RC01 Text en Copyright © 2013 Hospital das Clínicas da FMUSP http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Rapid Communication Izzo, Giselle Forlenza, Orestes V. dos Santos, Bernardo Bertolucci, Paulo H. F. Ojopi, Elida B. Gattaz, Wagner F. Kerr, Daniel Shikanai Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title | Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title_full | Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title_fullStr | Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title_full_unstemmed | Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title_short | Single-nucleotide polymorphisms of GSK3B, GAB2 and SORL1 in late-onset Alzheimer's disease: interactions with the APOE genotype |
title_sort | single-nucleotide polymorphisms of gsk3b, gab2 and sorl1 in late-onset alzheimer's disease: interactions with the apoe genotype |
topic | Rapid Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584260/ https://www.ncbi.nlm.nih.gov/pubmed/23525328 http://dx.doi.org/10.6061/clinics/2013(02)RC01 |
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