Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences

Induced pluripotent stem (iPS) cells, are a type of pluripotent stem cell derived from adult somatic cells. They have been reprogrammed through inducing genes and factors to be pluripotent. iPS cells are similar to embryonic stem (ES) cells in many aspects. This review summarizes the recent progress...

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Detalles Bibliográficos
Autores principales: Ye, Lei, Swingen, Cory, Zhang, Jianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584308/
https://www.ncbi.nlm.nih.gov/pubmed/22935022
http://dx.doi.org/10.2174/157340313805076278
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author Ye, Lei
Swingen, Cory
Zhang, Jianyi
author_facet Ye, Lei
Swingen, Cory
Zhang, Jianyi
author_sort Ye, Lei
collection PubMed
description Induced pluripotent stem (iPS) cells, are a type of pluripotent stem cell derived from adult somatic cells. They have been reprogrammed through inducing genes and factors to be pluripotent. iPS cells are similar to embryonic stem (ES) cells in many aspects. This review summarizes the recent progresses in iPS cell reprogramming and iPS cell based therapy, and describe patient specific iPS cells as a disease model at length in the light of the literature. This review also analyzes and discusses the problems and considerations of iPS cell therapy in the clinical perspective for the treatment of disease.
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spelling pubmed-35843082014-02-01 Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences Ye, Lei Swingen, Cory Zhang, Jianyi Curr Cardiol Rev Article Induced pluripotent stem (iPS) cells, are a type of pluripotent stem cell derived from adult somatic cells. They have been reprogrammed through inducing genes and factors to be pluripotent. iPS cells are similar to embryonic stem (ES) cells in many aspects. This review summarizes the recent progresses in iPS cell reprogramming and iPS cell based therapy, and describe patient specific iPS cells as a disease model at length in the light of the literature. This review also analyzes and discusses the problems and considerations of iPS cell therapy in the clinical perspective for the treatment of disease. Bentham Science Publishers 2013-02 2013-02 /pmc/articles/PMC3584308/ /pubmed/22935022 http://dx.doi.org/10.2174/157340313805076278 Text en © 2013 Bentham Science Publishers http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Ye, Lei
Swingen, Cory
Zhang, Jianyi
Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title_full Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title_fullStr Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title_full_unstemmed Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title_short Induced Pluripotent Stem Cells and Their Potential for Basic and Clinical Sciences
title_sort induced pluripotent stem cells and their potential for basic and clinical sciences
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584308/
https://www.ncbi.nlm.nih.gov/pubmed/22935022
http://dx.doi.org/10.2174/157340313805076278
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