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Safety, pharmacokinetics and resistant variants of telaprevir alone for 12 weeks in hepatitis C virus genotype 1b infection
Background: Telaprevir in combination with peginterferon and ribavirin is a promising advancement in chronic hepatitis C treatment. However, the safety, tolerability, pharmacokinetics and antiviral profiles of telaprevir alone beyond 2 weeks have not been studied. Methods: In a phase 1b study in Jap...
Autores principales: | Yamada, I, Suzuki, F, Kamiya, N, Aoki, K, Sakurai, Y, Kano, M, Matsui, H, Kumada, H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584515/ https://www.ncbi.nlm.nih.gov/pubmed/22239508 http://dx.doi.org/10.1111/j.1365-2893.2011.01514.x |
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