Aberrant methylation of PSD disturbs Rac1-mediated immune responses governing neutrophil chemotaxis and apoptosis in ulcerative colitis-associated carcinogenesis

We previously reported that the Pleckstrin and Sec7 domain-containing (PSD) gene is preferentially methylated in patients with ulcerative colitis (UC) who developed colorectal cancer (CRC), and is implicated in UC-associated carcinogenesis through its inhibition of apoptosis. This study aimed to det...

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Detalles Bibliográficos
Autores principales: KATO, TAKAHARU, SUZUKI, KOICHI, OKADA, SHINICHIRO, KAMIYAMA, HIDENORI, MAEDA, TAKAFUMI, SAITO, MASAAKI, KOIZUMI, KEI, MIYAKI, YUICHIRO, KONISHI, FUMIO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584566/
https://www.ncbi.nlm.nih.gov/pubmed/22179719
http://dx.doi.org/10.3892/ijo.2011.1301

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