NVP-BKM120, a novel PI3K inhibitor, shows synergism with a STAT3 inhibitor in human gastric cancer cells harboring KRAS mutations

Aberrations of Phosphoinositide 3-kinase (PI3K)/AKT signaling are frequently observed in many types of cancer, promoting its emergence as a promising target for cancer treatment. PI3K can become activated by various pathways, one of which includes RAS. RAS can not only directly activate the PI3K/AKT...

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Detalles Bibliográficos
Autores principales: PARK, EUNJU, PARK, JINAH, HAN, SAE-WON, IM, SEOCK-AH, KIM, TAE-YOU, OH, DO-YOUN, BANG, YUNG-JUE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584651/
https://www.ncbi.nlm.nih.gov/pubmed/22159814
http://dx.doi.org/10.3892/ijo.2011.1290

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584651/
https://www.ncbi.nlm.nih.gov/pubmed/22159814
http://dx.doi.org/10.3892/ijo.2011.1290

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