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Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water

BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses o...

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Autores principales: Keeler, Shamus P, Lebarbenchon, Camille, Stallknecht, David E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584729/
https://www.ncbi.nlm.nih.gov/pubmed/23289857
http://dx.doi.org/10.1186/1743-422X-10-13
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author Keeler, Shamus P
Lebarbenchon, Camille
Stallknecht, David E
author_facet Keeler, Shamus P
Lebarbenchon, Camille
Stallknecht, David E
author_sort Keeler, Shamus P
collection PubMed
description BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses of three subtypes (H3N8, H4N6, and H8N4). RESULTS: We experimentally estimated the loss of infectivity over time in three different types of water: distilled, filtered surface water, and intact surface water. All viruses persisted longest in distilled water followed by filtered surface water with markedly reduced durations of persistence observed in the intact surface water. Strain-related variations were observed in distilled and filtered surface water but limited variation was observed in the intact surface water. CONCLUSIONS: Our findings suggest that the role of surface water for long-term (between years) maintenance of AI viruses in the environment may be limited, and suggest that the physico-chemical characteristics of water, as well as microorganisms, may be of strong importance. Results also indicate that the extent of strain-related variation observed in distilled water may overestimate persistence abilities for IA viruses in the wild and supports the need to develop experiments that account for these effects to assess subtype, genotype, as well as spatial and temporal variation in the persistence of IA viruses in aquatic habitats.
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spelling pubmed-35847292013-03-02 Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water Keeler, Shamus P Lebarbenchon, Camille Stallknecht, David E Virol J Research BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses of three subtypes (H3N8, H4N6, and H8N4). RESULTS: We experimentally estimated the loss of infectivity over time in three different types of water: distilled, filtered surface water, and intact surface water. All viruses persisted longest in distilled water followed by filtered surface water with markedly reduced durations of persistence observed in the intact surface water. Strain-related variations were observed in distilled and filtered surface water but limited variation was observed in the intact surface water. CONCLUSIONS: Our findings suggest that the role of surface water for long-term (between years) maintenance of AI viruses in the environment may be limited, and suggest that the physico-chemical characteristics of water, as well as microorganisms, may be of strong importance. Results also indicate that the extent of strain-related variation observed in distilled water may overestimate persistence abilities for IA viruses in the wild and supports the need to develop experiments that account for these effects to assess subtype, genotype, as well as spatial and temporal variation in the persistence of IA viruses in aquatic habitats. BioMed Central 2013-01-07 /pmc/articles/PMC3584729/ /pubmed/23289857 http://dx.doi.org/10.1186/1743-422X-10-13 Text en Copyright ©2013 Keeler et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Keeler, Shamus P
Lebarbenchon, Camille
Stallknecht, David E
Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title_full Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title_fullStr Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title_full_unstemmed Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title_short Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
title_sort strain-related variation in the persistence of influenza a virus in three types of water: distilled water, filtered surface water, and intact surface water
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584729/
https://www.ncbi.nlm.nih.gov/pubmed/23289857
http://dx.doi.org/10.1186/1743-422X-10-13
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