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Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water
BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses o...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584729/ https://www.ncbi.nlm.nih.gov/pubmed/23289857 http://dx.doi.org/10.1186/1743-422X-10-13 |
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author | Keeler, Shamus P Lebarbenchon, Camille Stallknecht, David E |
author_facet | Keeler, Shamus P Lebarbenchon, Camille Stallknecht, David E |
author_sort | Keeler, Shamus P |
collection | PubMed |
description | BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses of three subtypes (H3N8, H4N6, and H8N4). RESULTS: We experimentally estimated the loss of infectivity over time in three different types of water: distilled, filtered surface water, and intact surface water. All viruses persisted longest in distilled water followed by filtered surface water with markedly reduced durations of persistence observed in the intact surface water. Strain-related variations were observed in distilled and filtered surface water but limited variation was observed in the intact surface water. CONCLUSIONS: Our findings suggest that the role of surface water for long-term (between years) maintenance of AI viruses in the environment may be limited, and suggest that the physico-chemical characteristics of water, as well as microorganisms, may be of strong importance. Results also indicate that the extent of strain-related variation observed in distilled water may overestimate persistence abilities for IA viruses in the wild and supports the need to develop experiments that account for these effects to assess subtype, genotype, as well as spatial and temporal variation in the persistence of IA viruses in aquatic habitats. |
format | Online Article Text |
id | pubmed-3584729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35847292013-03-02 Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water Keeler, Shamus P Lebarbenchon, Camille Stallknecht, David E Virol J Research BACKGROUND: The persistence of influenza A (IA) virus in aquatic habitats has been demonstrated to be a determinant for virus transmission dynamics in wild duck populations. In this study, we investigated virus strain-related variation in persistence in water for nine wild duck isolated IA viruses of three subtypes (H3N8, H4N6, and H8N4). RESULTS: We experimentally estimated the loss of infectivity over time in three different types of water: distilled, filtered surface water, and intact surface water. All viruses persisted longest in distilled water followed by filtered surface water with markedly reduced durations of persistence observed in the intact surface water. Strain-related variations were observed in distilled and filtered surface water but limited variation was observed in the intact surface water. CONCLUSIONS: Our findings suggest that the role of surface water for long-term (between years) maintenance of AI viruses in the environment may be limited, and suggest that the physico-chemical characteristics of water, as well as microorganisms, may be of strong importance. Results also indicate that the extent of strain-related variation observed in distilled water may overestimate persistence abilities for IA viruses in the wild and supports the need to develop experiments that account for these effects to assess subtype, genotype, as well as spatial and temporal variation in the persistence of IA viruses in aquatic habitats. BioMed Central 2013-01-07 /pmc/articles/PMC3584729/ /pubmed/23289857 http://dx.doi.org/10.1186/1743-422X-10-13 Text en Copyright ©2013 Keeler et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Keeler, Shamus P Lebarbenchon, Camille Stallknecht, David E Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title | Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title_full | Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title_fullStr | Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title_full_unstemmed | Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title_short | Strain-related variation in the persistence of influenza A virus in three types of water: distilled water, filtered surface water, and intact surface water |
title_sort | strain-related variation in the persistence of influenza a virus in three types of water: distilled water, filtered surface water, and intact surface water |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584729/ https://www.ncbi.nlm.nih.gov/pubmed/23289857 http://dx.doi.org/10.1186/1743-422X-10-13 |
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