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Therapeutic targeting of cancer cell cycle using proteasome inhibitors
Proteasomes are multicatalytic protease complexes in the cell, involved in the non-lysosomal recycling of intra-cellular proteins. Proteasomes play a critical role in regulation of cell division in both normal as well as cancer cells. In cancer cells this homeostatic function is deregulated leading...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584802/ https://www.ncbi.nlm.nih.gov/pubmed/23268747 http://dx.doi.org/10.1186/1747-1028-7-26 |