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2-Triazenoazaindoles: A novel class of triazenes inducing transcriptional down-regulation of EGFR and HER-2 in human pancreatic cancer cells

Pancreatic cancer is a complex malignancy arising from the accumulation of genetic and epigenetic defects in the affected cells. Standard chemotherapy for patients with advanced disease shows only modest effects and is associated with considerable toxicity. Overexpression or aberrant activation of m...

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Detalles Bibliográficos
Autores principales:	KREUTZER, JAN N., SALVADOR, ALESSIA, DIANA, PATRIZIA, CIRRINCIONE, GIROLAMO, VEDALDI, DANIELA, LITCHFIELD, DAVID W., ISSINGER, OLAF-GEORG, GUERRA, BARBARA
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2011
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584806/ https://www.ncbi.nlm.nih.gov/pubmed/22134789 http://dx.doi.org/10.3892/ijo.2011.1272

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