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IL-6-induced epithelial-mesenchymal transition promotes the generation of breast cancer stem-like cells analogous to mammosphere cultures

Recently, the inflammatory cytokine IL-6 has been reported as a potent inducer of epithelial-mesenchymal transition (EMT) in breast cancer cells with an epithelial phenotype. Furthermore, EMT induces stem cell features in normal and transformed mammary cells. We explored whether IL-6-induced EMT pro...

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Detalles Bibliográficos
Autores principales: XIE, GUOZHU, YAO, QIWEI, LIU, YING, DU, SHASHA, LIU, AIHUA, GUO, ZHAOZE, SUN, AIMIN, RUAN, JIAN, CHEN, LONGHUA, YE, CHANGSHENG, YUAN, YAWEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584811/
https://www.ncbi.nlm.nih.gov/pubmed/22134360
http://dx.doi.org/10.3892/ijo.2011.1275