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Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy
This study examined the role of the immunosuppressive enzyme indoleamine-2,3-dioxygenase (IDO) in ovarian cancer progression, and the possible application of this enzyme as a target for ovarian cancer therapy. We transfected a short hairpin RNA vector targeting IDO into the human ovarian cancer cell...
Autores principales: | WANG, DONGDONG, SAGA, YASUSHI, MIZUKAMI, HIROAKI, SATO, NAOTO, NONAKA, HIROAKI, FUJIWARA, HIROYUKI, TAKEI, YUJI, MACHIDA, SHIZUO, TAKIKAWA, OSAMU, OZAWA, KEIYA, SUZUKI, MITSUAKI |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584823/ https://www.ncbi.nlm.nih.gov/pubmed/22179492 http://dx.doi.org/10.3892/ijo.2011.1295 |
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