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Function prediction from networks of local evolutionary similarity in protein structure
BACKGROUND: Annotating protein function with both high accuracy and sensitivity remains a major challenge in structural genomics. One proven computational strategy has been to group a few key functional amino acids into templates and search for these templates in other protein structures, so as to t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584919/ https://www.ncbi.nlm.nih.gov/pubmed/23514548 http://dx.doi.org/10.1186/1471-2105-14-S3-S6 |