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Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans

The normal aging process is associated with stereotyped changes in gene expression, but the regulators responsible for these age-dependent changes are poorly understood. Using a novel genomics approach, we identified HOX co-factor unc-62 (Homothorax) as a developmental regulator that binds proximal...

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Detalles Bibliográficos
Autores principales: Van Nostrand, Eric L., Sánchez-Blanco, Adolfo, Wu, Beijing, Nguyen, Andy, Kim, Stuart K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585033/
https://www.ncbi.nlm.nih.gov/pubmed/23468654
http://dx.doi.org/10.1371/journal.pgen.1003325

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