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Roles of the Developmental Regulator unc-62/Homothorax in Limiting Longevity in Caenorhabditis elegans
The normal aging process is associated with stereotyped changes in gene expression, but the regulators responsible for these age-dependent changes are poorly understood. Using a novel genomics approach, we identified HOX co-factor unc-62 (Homothorax) as a developmental regulator that binds proximal...
Autores principales: | Van Nostrand, Eric L., Sánchez-Blanco, Adolfo, Wu, Beijing, Nguyen, Andy, Kim, Stuart K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585033/ https://www.ncbi.nlm.nih.gov/pubmed/23468654 http://dx.doi.org/10.1371/journal.pgen.1003325 |
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