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HIV-1 Viral Infectivity Factor (Vif) Alters Processive Single-stranded DNA Scanning of the Retroviral Restriction Factor APOBEC3G

APOBEC3G is a retroviral restriction factor that can inhibit the replication of human immunodeficiency virus, type 1 (HIV-1) in the absence of the viral infectivity factor (Vif) protein. Virion-encapsidated APOBEC3G can deaminate cytosine to uracil in viral (−)DNA, which leads to hypermutation and i...

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Detalles Bibliográficos
Autores principales:	Feng, Yuqing, Love, Robin P., Chelico, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	DNA and Chromosomes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585047/ https://www.ncbi.nlm.nih.gov/pubmed/23316055 http://dx.doi.org/10.1074/jbc.M112.421875

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