HLA-A2 and B35 Restricted Hantaan Virus Nucleoprotein CD8(+) T-Cell Epitope-Specific Immune Response Correlates with Milder Disease in Hemorrhagic Fever with Renal Syndrome

BACKGROUND: Hantaan virus (HTNV) infection in humans is a serious public health concern in Asia. A potent T cell activation peptide vaccine from HTNV structure protein represents a promising immunotherapy for disease control. However, the T cell epitopes of the HTNV restricted by the HLA alleles and...

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Detalles Bibliográficos
Autores principales: Ma, Ying, Wang, Jiuping, Yuan, Bin, Wang, Meiliang, Zhang, Yun, Xu, Zhuwei, Zhang, Chunmei, Zhang, Yusi, Liu, Bei, Yi, Jing, Yang, Kun, Yang, Angang, Zhuang, Ran, Jin, Boquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585118/
https://www.ncbi.nlm.nih.gov/pubmed/23469304
http://dx.doi.org/10.1371/journal.pntd.0002076

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