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Genome-Wide Analysis Points to Roles for Extracellular Matrix Remodeling, the Visual Cycle, and Neuronal Development in Myopia

Myopia, or nearsightedness, is the most common eye disorder, resulting primarily from excess elongation of the eye. The etiology of myopia, although known to be complex, is poorly understood. Here we report the largest ever genome-wide association study (45,771 participants) on myopia in Europeans....

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Detalles Bibliográficos
Autores principales: Kiefer, Amy K., Tung, Joyce Y., Do, Chuong B., Hinds, David A., Mountain, Joanna L., Francke, Uta, Eriksson, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585144/
https://www.ncbi.nlm.nih.gov/pubmed/23468642
http://dx.doi.org/10.1371/journal.pgen.1003299