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Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

Influenza viruses (IV) cause pneumonia in humans with progression to lung failure and fatal outcome. Dysregulated release of cytokines including type I interferons (IFNs) has been attributed a crucial role in immune-mediated pulmonary injury during severe IV infection. Using ex vivo and in vivo IV i...

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Detalles Bibliográficos
Autores principales: Högner, Katrin, Wolff, Thorsten, Pleschka, Stephan, Plog, Stephanie, Gruber, Achim D., Kalinke, Ulrich, Walmrath, Hans-Dieter, Bodner, Johannes, Gattenlöhner, Stefan, Lewe-Schlosser, Peter, Matrosovich, Mikhail, Seeger, Werner, Lohmeyer, Juergen, Herold, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585175/
https://www.ncbi.nlm.nih.gov/pubmed/23468627
http://dx.doi.org/10.1371/journal.ppat.1003188